In addition to being known for experimenting with many musical genres, mostly rock, psychedelic and electronica, he is known for his political views and for being an anti-war, anti-nuclear, and environmental activist.

[7] When he was around the age of 17, then in high school, Sugizo with Shinya on drums and Tezya on vocals formed a power metal band called Pinocchio,[8][9] where he played as the bassist.

With the addition of Ryuichi Kawamura, vocalist from the band Slaughter, the five formed the visual kei rock unit Lunacy.

Since J was already the bass player and Inoran preferred to play rhythm guitar, Sugizo became the lead guitarist and took on his stage name, which he believes Shinya came up with.

They became one of the most famous rock bands in Japan, selling more than ten million records, as well as performing in China and Taiwan.

[16] It was followed by his first solo tour Abstract Day which lasted until the final performance in August at Akasaka Blitz, where he was joined by DJ Krush,[17] Masami Tsuchiya and members of Japan.

[16][19] As Luna Sea resumed activities, until the band's disbandment, Sugizo collaborated in the studio with actress Miki Nakatani[22] and singers Miu Sakamoto[23] and Vivian Hsu, among others.

[24][25] Around late 2001 he formed the solo project Sugizo & the Spank Your Juice, with whom he toured with until 2004 and released three singles; "Super Love", "Dear Life" and "No More Machineguns Play the Guitar", which entered top 50 on the charts.

[26] His acting career also continued in 2002, when he starred in Isao Yukisada's film Rock'n'roll Mishin, and the television series RedЯum, directed by Ken Nikai.

[32] On June 29, 2007, Anime Expo convention in Long Beach, California, hosted the debut performance of S.K.I.N, a supergroup consisting of Sugizo, Yoshiki, Gackt, and Miyavi.

[33][34] In July, Juno Reactor performed as the White Stage's main act on the final day of the Fuji Rock Festival.

[37] On March 28 and 29, 2008, Sugizo played at X Japan's two reunion concerts as a stand-in along Wes Borland and Richard Fortus for the deceased hide.

[41] The album featured various music genres, such as rock, trance, jazz, classic, bossa nova, among others, and spans his ten years of solo work.

[24] During the year, Sugizo wrote a song titled "Enola Gay", named after the Boeing B-29 bomber that dropped the atomic bomb on Hiroshima.

[42] He wrote the song to convey his feelings and thoughts toward the people who suffered from the aftermath of nuclear war, and to the cities of Hiroshima and Nagasaki.

[43] As well, that the bomb never must be dropped again, and as his live supporting drummer Greg Ellis is American, singer Origa Russian, and him Japanese, that people from former enemy states can be friends.

[43] Upon returning to Japan, on January 27 Sugizo released two digital singles, "Fatima" and "Do-Funk Dance",[49] another on February 24 entitled "Prana", which also topped the iTunes electronic charts,[50] and one more on March 31 named "Dear Spiritual Life".

[51] Sugizo was the music director and composer of the soundtrack for jidaigeki theatre stage play Nemuri Kyoshiro Buraihikae, featuring Gackt in the main role,[52] which ran for 120 performances across Japan.

The song was renamed "Missing Link" and was available for download in return for a donation on Mick's official website to help fund the expensive medical treatment.

On August 31, he and Luna Sea attended a press conference in Hong Kong, where they announced that they would be touring worldwide after 10 years of inactivity.

[58] From November 5 to 8, Sugizo teamed up with drummers Budgie, Leonard Eto and Mabi, and multi-instrumentalist Knox Chandler in Hong Kong, to participate in a project called "The Butterfly Effect: East-West Percussive Parade", as part of the New Vision Arts Festival.

[67][68] In 2012, besides being vastly involved with Luna Sea, two digital songs were released, titled "Final of the Messiah" and "Super Love 2012", followed by concerts.

[88] On March 11, he took part in the Peace on Earth event in Yoyogi Park for a memorial ceremony of the 2011 Tōhoku earthquake and tsunami.

[89] In April, he covered the track Bike, for Maaya Sakamoto's 20th anniversary tribute album,[90] and was scheduled to appear at the Tanz Too Noise Muzik Festival in Hong Kong, but the event was eventually cancelled.

[100] On March 11, 2016, he again participated in the free Peace on Earth event,[101] then appeared on Kazumi Watanabe's Guitar is Beautiful KW45 45th anniversary album with the tracks "Round Midnight" and "Island Hop".

[108] As a celebration of the 20th anniversary of his solo debut, Sugizo set out on a national tour,[109] with his new album, Oto released in November.

[113] At the end of 2017, Sugizo released a solo album titled Oneness M, featuring a different vocalist on each song, including for example Toshi of X Japan and Teru from Glay.

Aina the End (BiSH) covering "Hikari no Hate" (光の涯), which was originally on his album Oneness M with lyrics and vocals provided by Morrie.

[9][132] After the 2011 Tōhoku earthquake and tsunami, Sugizo continued to yearly volunteer and offer educational assistance to the locals of Ishinomaki and Minamisōma among others.

[140][141][142] His amps have changed often throughout his career but are generally high-end and boutique brands, including Fender, Marshall, Mesa/Boogie, Matchless, Bogner, Custom Audio Electronics, Divided by 13 and Koch.