[3] She is celebrated as the Melody Queen of South India, and is known by various affectionate titles: Bhava Gayika in Kerala, and Innisai Kuyil in Tamil Nadu.

[4] She is also known for her extensive history of collaboration with music composers like A. R. Rahman, Ilaiyaraja, M. M. Keeravani, Koti, Vidyasagar, Mani Sharma, and with the playback singers K. J. Yesudas, Hariharan, and S. P. Balasubrahmanyam, over the years.

Sujatha Mohan is the granddaughter of Paravoor T. K. Narayana Pillai, the first Chief Minister of the erstwhile State of Travancore–Cochin after India gained Independence.

[7] Mohan shot to fame in the seventies as Baby Sujatha, the schoolgirl who regularly used to sing with K. J. Yesudas in his stage shows all over the world.

She debuted in Tamil through the song "Kaadhal Oviyam Kandein" from Kavikuyil (1977), tuned in Hameer Kalyani raga by Illayaraja, but it was not included in the film.

Then Rahman got her to sing "Pudhu Vellai Mazhai" from Mani Ratnam's 1992 film Roja, which became one of the biggest hit songs in India.

She has also recorded some songs in Hindi, including "Dil Hai Sanam" (the Hindi version of "Thee Thee") from Chor Chor (Thiruda Thiruda), "Ishq Bina" from Taal, "Hai Jaana" from Pukar and "Ishwar Allah" from Earth, and provided backing vocals for the song "Tum Ho Meri Nigahom" from Kabhi Na Kabhi, all of them composed by A. R. Rahman.