Sultantepe is a neighbourhood in the municipality and district of Üsküdar, Istanbul Province, Turkey.

[4] During Ottoman times, according to one source, the neighborhood was selected as a residence by a woman in Suleiman the Magnificent's court, Hacı Hesna Hatun (Lady Hesna the Hajji), the nursemaid of his daughter Mihrimah Sultan.

Retail businesses are concentrated along Selmani Pak Avenue on the southern edge of the neighborhood and around the square on top of the hill.

It played a role in the Turkish War of Independence as a refuge and meeting place for members of the resistance, communications center, hospital, and weapons depot.

At the entrance to the cemetery is the tomb of Ali Rıza Efendi, about whom nothing is known except that he died at age 15.