The series centers on FBI special agents Dana Scully (Gillian Anderson) and her new partner John Doggett (Robert Patrick)—following the alien abduction of her former partner, Fox Mulder (David Duchovny)—who work on cases linked to the paranormal, called X-Files.

Due to the presence of his "biker buddy" Michael Bowen, series co-star Robert Patrick was noticeably more energized than usual to film the episode, according to Gillian Anderson.

After a skirmish with the guards, he is placed in a large room with cinder blocks for walls and a solid steel door.

Dana Scully (Gillian Anderson) and John Doggett (Robert Patrick) are informed that Chase was killed with an armor-piercing round, which appears to have entered the room through the air vent in the ceiling.

Tammi Peyton enters AAA-1 Surekill Exterminators and plays her message machine, which contains the victim's phone call from the previous night.

Later, Scully and Doggett investigate the Chase residence and find a bullet casing on the floor.

Eventually, Scully proposes that the killer can perceive wave lengths of light not visible with an ordinary human eye, allowing him to virtually see through walls.

Dwight claims he runs a clean business, but Scully pulls out several folders containing invoices for Chase.

[1] "Surekill" was written by executive story editor Greg Walker, and marked his second script contribution to the series, after season seven's "Brand X".

[2] Although the episode was the eighth aired in the season, it was actually the ninth one filmed, as evidenced by its production number: 8ABX09.

[4] "Surekill" guest starred Michael Bowen, a "biker buddy" of series co-star Robert Patrick.

"[11] Robert Shearman and Lars Pearson, in their book Wanting to Believe: A Critical Guide to The X-Files, Millennium & The Lone Gunmen, rated the episode one star out of five.

The two derided the episode for being overly "dull", noting "you watch with open mouth amazement that writer Greg Walker can spin this premise out for forty-five minutes.

"[12] Paula Vitaris from Cinefantastique gave the episode a negative review and awarded it one-and-a-half stars out of four.