Suresh Krishna was born on 5 April 1973, the youngest of six children, to Balakrishna Panicker and Parvathy in the temple town of Guruvayoor in Thrissur district.

[3] He was working in Tamil films and television from Chennai when he was offered a chance to debut in Malayalam, acting in the serial Sthree Janmam.

Since then he has acted in a slew of Malayalam films with major directors and stars, including; Kamal (in Manju poloru Penkutty and Rapakkal ); Santhosh Sivan (in Ananthabhadram), Ranjith ( in Paleri Manikyam, Kerala Cafe and Indian Rupee), Joshiy (Christian Brothers ), Shaji N. Karun (in Kutty Srank ) and Hariharan in his film PazhassiRaja.

In 2024, he found sudden new popularity on social media, following a wave of memes highlighting the nature of deceit and manipulation done by the characters he had portrayed, branding him the title 'Convincing star'.

[6] Suresh has also become a producer through Thakkali Films, along with actor Biju Menon, director Shajoon Kariyal, scriptwriter Sachi and cinematographer P. Sukumar.