[1][3][4] The church is across the passenger-ferry pier of Kuzguncuk in Üsküdar district on the Asian coast of Bosphorus in Istanbul, Turkey.

[1][3] Strict rules of construction and renovation imposed by the Ottoman Empire are seen as the cause for the lack of architectural aesthetics of Armenian churches in Istanbul built mostly during that era.

The Surp Krikor Lusavoriç Armenian Church in Kuzguncuk makes an exception with its cruciform plan, Byzantine dome, and reliefs.

[1][3] The wooden guard rail in front of the altar is decorated with flower and leaf figures made by Kalust Agha Kemhacyan, who provided timber to the Sultan's court.

[1] In 1853, a co-educational school named Lusavoriçyan was established in a building on the same land with the church to meet the educational needs of the growing Armenian population in the Kuzguncuk area.

[2][5] A group of Christian, Jewish, and Muslim students and adults visited the church in February 2008 as part of a social activity organized by the local women residents of the three religions.