The purpose of the SSC is to create an international collaborative effort to improve the treatment of sepsis and reduce the high mortality rate associated with the condition.

As medicine becomes more advanced, with invasive procedures and immunosuppression, the incidence of sepsis is likely to increase even more.

In 2020, the campaign produced Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019.

Each hospital's sepsis protocol may be customized, but it must meet the standards created by the bundle.

The first 6-hour SSC Resuscitation Bundle includes: Further management is centered on Early Goal Directed Therapy (EGDT).