Suze-la-Rousse (French pronunciation: [syz la ʁus]; Occitan: Susa la Rossa) is a commune in the Drôme department in southeastern France, situated in the heart of the Rhône Valley vineyards Suze-la-Rousse is located 10 km (6.2 mi) southeast of Saint-Paul-Trois-Châteaux and 18 km (11 mi) north of Orange.

It extends over the left bank of the river Lez and commands an uninterrupted view of the Mont Ventoux, the Lance mountains, and the foothills of the Dauphiné Alps.

The neighbouring settlements are Bollène, Rochegude, Tulette, Sainte-Cécile-les-Vignes, Bouchet, La Baume-de-Transit, Solérieux et Saint-Restitut.

Suze castle was built in the 12th century by the princes of Orange on the site of a hunting lodge given by Charlemagne to his cousin Guillaume de Gellone.

The facility, with its laboratories and tasting rooms is unique in Europe, and offers courses in oenology, marketing, and management for the wine industry.