Svatobořice-Mistřín is a municipality in Hodonín District in the South Moravian Region of the Czech Republic.

Svatobořice-Mistřín consists of two municipal parts (in brackets population according to the 2021 census):[2] Svatobořice-Mistřín is located about 13 kilometres (8 mi) north of Hodonín and 41 km (25 mi) southeast of Brno.

The highest point is the hill Záviště at 256 m (840 ft) above sea level.

The first written mention of Mistřín is in a deed of King Ottokar I of Bohemia from 1228.

The main landmark of Mistřín is the Church of the Visitation of the Virgin Mary.