The Women's 100 metre freestyle event at the 2010 Commonwealth Games took place on 5 and 6 October 2010, at the SPM Swimming Pool Complex.
[1] Six heats were held, with most containing the maximum number of swimmers (eight).
The heat in which a swimmer competed did not formally matter for advancement, as the swimmers with the top sixteen times advanced to the semifinals and the top eight times from the semi-finals qualified for the finals.
[2] The Heats started on 9:00 local time.
[3]