The medley relay swimming events for the 2020 Summer Paralympics took place at the Tokyo Aquatics Centre from September 2 to September 3, 2021.
[1] The following is a summary of the medals awarded across all 4 × 100 metre medley relay events.
Medals are also awarded to swimmers who have swum in heats.
[3] a Swimmers who participated in the heats only and received medals.
The following were the results of the finals only of each of the medley relay events in each of the classifications.