In October 2006, the New York appeals court ruled in favor of Swiss Re, stating that the destruction of the twin towers was a single event rather than two, limiting coverage to $3.5 billion.

[10] Swiss Re acquired the GE Insurance Solutions property/casualty business in 2006, which made it the world's largest reinsurer.

[13] In May 2016, the Fort McMurray Canadian wildfires caused estimated damages of up to CAD10 billion, with Swiss Re having the most exposure among reinsurers.

[14] Swiss Re's Admin Re subsidiary began with the acquisition on 1 July 2004 of Life Assurance Holding Corporation in the UK.

[15] On 31 October 2008, Swiss Re completed a £762 million acquisition of Barclays PLC's subsidiary Barclays Life Assurance Company Ltd.[16] In June 2014, the company, through Admin Re, acquired the UK pensions business of HSBC Life (UK) Limited worth £4.2 billion.

At the same time, the board of directors assured investors that the company is only minimally exposed to losses during the Ukraine crisis.

The landmark London skyscraper, designed by architect Norman Foster and popularly known as "the gherkin", was sold in February 2007 for over £600 million to IVG Immobilien AG of Germany and the Evans Randall property investment firm.