The hospital is operated by the Seventh-day Adventist Church, whose South Pacific Division headquarters are located in the immediate vicinity of the San.

As a not-for-profit health care facility, 2,200 staff and 700 accredited medical officers provide services for more than 50,000 inpatients and over 160,000 outpatients annually at the San.

[5] It opened in Wahroonga on 1 January 1903 with a bed capacity of 70 and was known as a ‘home of health’ and as a place where people learned to stay well.

[4] In 2006 the San won the prestigious national Australian Private Hospital Award for Clinical Excellence (70 beds and over).

The San also become home to the Southern Hemisphere's first Dual Source Computerised Tomography Scanner in the same year.