Syed Naguib made his ATP main draw debut at the 2012 Proton Malaysian Open in the doubles competition.

At age 16, he was selected for further training through a national pilot tennis programme under Albert Portas High Performance Camp in Barcelona, Spain.

[6] In the 2013 ATP Malaysian Open, he paired with Indian tennis player, Yuki Bhambri, but lost to Julien Benneteau-Nenad Zimonjić in the first round.

[9] At the 2015 Southeast Asian Games, Syed Mohd Agil Syed Naguib, made the country proud after bagging Malaysia their second tennis medal, winning a Bronze medal in a match against Singapore for a team event.

[5] In 2019, he won the male doubles category alongside partner, Mohd Assri Merzuki[11] at the national circuit.