"Symphony 2000" is the lead single released from EPMD's sixth album, Out of Business.

The song was produced by Erick Sermon and featured verses from EPMD's labelmates, Method Man & Redman and Lady Luck.

"Symphony 2000" was EPMD's last charting single making it to the R&B and rap charts.

The song sampled the famous main title song from the movie Uccellacci e Uccellini, directed by italian director Pier Paolo Pasolini and composed by Ennio Morricone.

The song was sung by Italian actor and singer Domenico Modugno.