In the early 20th century, the Jewish community gathered in the Jean-Jacques Mercier [fr] building on Rue du Grand-Chêne in Lausanne.

[2] Upon the death of French merchant Daniel Iffla ("Osiris"), the City Council of Lausanne received a bequest of 50,000 francs.

[5] The building was designed by Vaudois architects Charles Bonjour, Adrien van Dorsser and Oscar Oulevey and inaugurated on November 7, 1910.

[2] After WWII, the community grew and integrated Sepharadi Jews, which requested unity in the rites and the use of the synagogue.

The paintings were made by Otto Alfred Briffod and the stained-glass windows were manufactured by the workshop Guignard & Schmid.