[1][2] Synechiae can be caused by ocular trauma, iritis or iridocyclitis and may lead to certain types of glaucoma.

Anterior synechia causes closed angle glaucoma, which means that the iris closes the drainage way of aqueous humour which in turn raises the intraocular pressure.

Posterior synechia can be observed in cases of anterior uveitis secondary to severe to moderate bacterial keratitis.

Mydriatic or cycloplegic agents, such as topical homatropine, which is similar in action to atropine, are useful in breaking and preventing the formation of posterior synechia by keeping the iris dilated and away from the crystalline lens.

If the pupil can be fully dilated during the treatment of iritis, the prognosis for recovery from synechia is good.