Synophis is a genus of snakes in the subfamily Dipsadinae of the family Colubridae.

The genus is native to northwestern South America.

Snakes of the genus Synophis have unusual scalation on the top of the head.

[1] The genus Synophis contains the following nine species which are recognized as being valid.

[2] Nota bene: A binomial authority in parentheses indicates that the species was originally described in a genus other than Synophis.