In the 16th century, the Catholics of the Latin Church came in contact with the Indian Christians through the Portuguese merchants and missionaries.

Later, on 20 September 1930, a group headed by Geevarghese Ivanios lead the reunion movement and returned to the Catholic Church.

To cope up with the tremendous growth of the church the Major Archeparchy of Trivandrum was ramified and a new Eparchy of Pathanamthitta was formed.

The diocesan area is basically hilly in nature including a considerable number of tribal colonies.

The Exarcate of the United States got its first bishop Thomas Eusebius from the Sacred Heart Malankara Catholic Church in Mylapra the Eparch of Pathanamthitta.