In addition to her status as an original cast member of the Fox sketch comedy series In Living Color (1990–1994), Keymáh is also known for her roles as Erica Lucas on the CBS sitcom Cosby (1996–2000), Tanya Baxter on the Disney Channel sitcom That's So Raven (2003–2005), and as the star and host on the Keymáh Network sketch variety show The Cool Crystal Show (2020–present).

[3] Born Crystal Walker on October 13, 1962, in Chicago, Illinois, at Cook County Hospital, Keymáh was raised Catholic on the city's South Side.

In this humorous, tear jerking, thought-provoking theatrical production, Keymáh champions societal issues that are as relevant today as they were when the show debuted to sold out crowds at Chicago's South Shore Cultural Center in 1991.

About her work in this show critics have said: "Keymáh is a Charismatic Actress... Chameleonic and Effervescent" – Los Angeles Times;"...Beyond Superlatives; She's Phenomenal!"

– Earl Calloway, Chicago Defender; "Much More Than Comedy"- Lisa M. Pancia, New York Vignette; "...a Delightful, Multitalented Performer whose ability to create believable characters on stage is a Wonder to Behold"- Nat Colley, Los Angeles Reader; "Keymáh is Magnificent" – Linda Armstrong, Amsterdam News;"...Keymáh's Poignant, Detailed Portrayals are Never Less Than Magnificent"- Randy Trabitz, Los Angeles Weekly.

Keymáh is an avid gardener and a vegetarian,[10] as well as an active, Golden Life Member of Delta Sigma Theta sorority.

[11] Keymáh's brother is former Commander of the DC US Army National Guard, current Sergeant at Arms of the United States House of Representatives, the Honorable Major General William J.

She also contributed essays to "The HBCU Experience Book," "Dining with the Ancestors: When Heroes Come to Dinner," and "The Burden: African Americans and the Enduring Impact of Slavery.

[20][21] She has presented her "Tools of the Trade" actors preparation workshops at theatre festivals and other events in the United States,[22][23] and she has lectured abroad.

[24] Her residency included directing Pearl Cleage's The Nacirema Society Requests Your Presence at a Celebration of Their First 100 Years, teaching an Acting for the Camera course, and providing industry workshops and mentoring students.