Tam Doan's family includes father, mother and younger sister Kristine Sa.

At the end of 1997, musician Tích Hà introduced Tam Doan to Vân Sơn Entertainment when the center needed a young vocalist.

Only in the first year, the name Tam Doan was known thanks to the appearance on 4 video programs (Van Son 7, 8, 9, 10) as well as through 2 CDs Tấm ảnh không hồn and Chuyến tàu hoàng hôn.

Tam Doan started appearing on the Thúy Nga stage from the show Paris by Night 63 with the theme Dòng Thời Gian.

In addition to singing, Tam Doan currently hosts a talkshow named after her and owns a cosmetic brand called D-One.