Tân Biên is a rural district of Tây Ninh province in the Southeast region of Vietnam.

[1] Aside from the Vietnamese majority, there are sizable minorities of ethnic Khmer and Cham people.

The name of the district literally means New Border; the area was part of the Khmer Empire until the 17th and 18th century when the southwards expansion of Vietnam under the Nguyễn lords brought it under the control of the Vietnamese people.

Production of rubber and sugarcane are the main economic activities in the district.

The Ministry of Culture and Information has declared parts of the district and neighbouring Tan Chau as historic sites of interest, claiming that the COSVN was located there during the Vietnam War.