It was a regular prison from 1895 to 1939 and again after 1945, but is best known for its role as an internment camp for various categories of individuals during World War II.
[1] Under the Ion Antonescu regime, Romanian Communist Party members were interned at Târgu Jiu during World War II.
Internees in 1943–1944 included Gheorghe Gheorghiu-Dej, Chivu Stoica, Mișu Dulgheru, Nicolae Ceaușescu, and Lucrețiu Pătrășcanu.
Gheorghiu-Dej arrived in late June 1943, was hospitalized with a stomach ailment from July to October and escaped with the help of a Soviet spy on the night of August 13–14, 1944.
Tudor Arghezi was detained there in 1943, having been arrested by the Gestapo for writing a pamphlet critical of Nazi German ambassador Manfred Freiherr von Killinger.