He is primarily known for his work directing popular television series such as Orphan Black, Xena: Warrior Princess, Gotham, Star Trek: Discovery, Longmire, 12 Monkeys, The Strain, and Spartacus.

In 2010, he received a Gemini Award nomination for directing the Discovery Channel made-for-television film Deadliest Sea.

He first worked in New Zealand with filmmakers Robert Tapert and Sam Raimi on Hercules: The Legendary Journeys (1995–1999) and subsequently directed several episodes of the spin-off TV series Xena: Warrior Princess (1996–2001).

[14] Throughout 2010s, Scott directed dozens of television episodes for series such as Spartacus (2012–2013), Bitten (2014–2015), Longmire (2014–present), Gotham (2014–2019), The Strain (2015–present) Dark Matter (2015–2018).

[15][16][17][18] In 2015, Scott directed episodes of the BBC America-Space television series Orphan Black, which, upon release, garnered a cult following,[19][20] and significant critical acclaim.

[21][22] In January 2015, it was announced that Scott was nominated by the Academy of Canadian Cinema & Television, Canada's equivalent to the Emmys, for his work on the show.

[26] The series, commissioned by Global Television Network as a British-Canadian co-production, stars Archie Panjabi, Christopher Plummer, Claire Forlani, Kris Holden-Ried, Rebecca Liddiard, and Shazad Latif, among others.

[34] In September 2011, it was announced that filmmaker Chris Columbus signed on to direct Scott's screenplay titled The Secret Lives of Road Crews for Paramount Pictures.