It imitates acoustic percussion: the bass drum, snare, toms, cymbal and hi-hat (open and closed).

[1] MusicRadar wrote that "the snare snaps and cracks, the kick offers a satisfying thud, and the metallic hats sizzle".

[1] Rhythms can be programmed using the sequencer, which includes controls for accents.

[1] The TR-606 was designed to be used with the Roland TB-303 bass synthesizer, and can be synchronized using DIN sync.

[1] The TR-606 was used by artists including the Sisters of Mercy, Orchestral Manoeuvres in the Dark, Skinny Puppy, Big Black, Autechre, Aphex Twin, Luke Vibert[1], Massive Attack.