The Taça Oswaldo Cruz (English: Oswaldo Cruz Cup) was a football tournament played between the national teams of Brazil and Paraguay, and contested from 1950 to 1976, albeit irregularly.

[1] It was organised by the Brazilian Sports Confederation and the Paraguayan Football Association with the purpose of promoting sporting exchange between the two countries.

The trophy was named after Oswaldo Cruz, a Brazilian physician, pioneer bacteriologist and epidemiologist,[2] and founder of the Oswaldo Cruz Institute.

[3] The competition was played in a two-legged format, with all the editions being won by Brazil.

From a total of 16 matches in 8 editions contested, Brazil won 11, with Paraguay only winning once.