His father, Ishiguro Tadanori was the Commander-in-chief of the medical corps of Imperial Japanese Army, and president of the Japan Red Cross.

During this time, he was very active in promoting rural relief measures,[3] and also served as Immigration Association President and Chairman of the Japan Agricultural Research Institute.

[4] However, Ishiguro was adamantly opposed to the Tripartite Alliance of Japan with Nazi Germany and Fascist Italy.

In 1946, after the surrender of Japan, as with all members of the prewar and wartime Japanese government, Ishiguro was purged by the American occupation authorities.

His promotion of social activism by bureaucrats in the ministry to favor small farmers came to be known as “Ishiguroism” within the Japanese bureaucracy.