[11][12] In August 2021, McGrath was named in Australia's squad for their series against India, which included a one-off day/night Test match as part of the tour.
[13] On 21 September 2021, in the first of the series' three WODI matches at Great Barrier Reef Arena, Mackay, Queensland, she swung the ball both ways while bowling, and really troubled some of India's best players, but did not take a wicket, and did not bat.
In the second WODI on 24 September 2021, also at Mackay, she claimed 3-45, and then made a career-best 74 in 77 balls, sharing in a partnership with Beth Mooney that helped to propel Australia from the lowest point in its run chase to a cliffhanging victory.
[15] In the first match of the series, a WT20I fixture, McGrath became the first Australian all-rounder to take three wickets and score more than 75 runs in a WT20I, finishing with figures of 3-26 and an unbeaten 91 off 49 balls.
[20] The following month, McGrath was named in Australia's team for the cricket tournament at the 2022 Commonwealth Games in Birmingham, England.