The first flight of the airline was from Bukhara to Dushanbe on 3 September 1924 by a Junkers F.13 aircraft, initiating the development of civil aviation in Tajikistan.

The Stalinabad airfield complex was created and the operation of new routes started over the Pamir mountain ranges.

One year later airports were built in Kulyab, Garm, Panj, and Dangara where regular flights were operated from Dushanbe.

Tajik aviation provided regular connections between the capital and the highland settlements in the hard-to-reach valleys of Vanch, Rushan, Shugnan, Bartang, Yagnob, and others, reducing the travel time of passengers of the mountain regions of the Pamirs, Karategin, blooming valleys of Vakhsh, Hissar by tens or hundreds of times.

In 1945, the Tajik Department of Civil Air Fleet (TU GVF) received new Lisunov Li-2 and Junkers Ju 52 aircraft.

Judging by the efficiency of the Yak-40 and An-28 aircraft utilization, the Tajik Civil Aviation Authority won first place in the USSR's Air Fleet.

In the 1990-1991 period, the aircraft-helicopter fleet of the aviation enterprise was expanded with Ilyushin Il-76 and Tupolev Tu-154M aircraft; and Mil Mi-8 helicopters.

Central Asia's first "Zardak" transponder was built and air service on the route Dushanbe-Ürümqi was opened.