Tajikistan sent a delegation to compete at the 2010 Winter Olympics in Vancouver, British Columbia, Canada from 12–28 February 2010.

The Tajikistani delegation consisted of a single athlete: alpine skier Andrei Drygin.

In the single-run race, he posted a time of 2 minutes and 4 seconds, which placed him 59th and last among the competitors who finished the competition.

Drygin posted a time of 1 minute and 38 seconds, good for 44th place out of 45 competitors to finish the race.

[12] In his final event, the slalom, held on 27 February, he failed to finish the first run in challenging weather conditions.