The Takechi family had originally been lower-class samurai, but five generations previously had become wealthy through farming and had successfully petitioned to have their official status changed.

In February 1859, the daimyō of Tosa Domain Yamauchi Yōdō, was forced from office and placed under house arrest by the tairō Ii Naosuke for his efforts to establish Hitotsubashi Yoshinobu as successor to the shogunate.

The sonnō jōi movement also spread quickly in Tosa, after many were alarmed by the arrival of the Perry Expedition in 1858 and what they perceived to be the weak response of the Tokugawa shogunate to this threat.

In May 1860, Takechi went on a tour of Kyushu and western Japan with a number of his closest disciples, and returned with some of the works of kokugaku scholar Hirata Atsutane, which further reinforced his belief in the Sonnō jōi movement.In April 1861, Takechi returned to Edo under the guise of practicing swordsmanship, but in reality to meet with like-minded samurai of various domains, including Katsura Kogōrō, Kusaka Genzui, and Takasugi Shinsaku of Chōshū, Kabayama Sanin from Satsuma and Iwama Kanpei from Mito.

Eventually, Takechi decided that his only course of action would be to assassinate Yoshida and to kidnap the young daimyō, Yamauchi Tomonori en route to Edo on his sankin kōtai.

He was sent to Edo as an official envoy of the Emperor, and was received in audience by Shogun Tokugawa Iemochi, which gave a vague and noncommittal response.

Yamauchi Yōdō meanwhile had been searching for the assassins of Yoshida Tōyō and arrested three members of the Tosa Kinnō-tō, who confessed to the crime under interrogation.

In September the following year, an uprising of samurai sympathetic to Takechi was suppressed and the roundup of Tosa Kinnō-tō members and supporters continued.

On July 3, 1865 four leaders of the Tosa Kinnoto were sentenced to death by decapitation, and Takechi was ordered to commit seppuku by Yamauchi Yōdō.

There was also an earthen-walled storehouse (no longer existent) and a storeroom, making it a typical goshi-yashiki residence of mid- to upper level samurai in the Edo Period.