Ōishi Sadashige constructed Takiyama Castle in 1521 to replace an earlier stronghold at Takatsuki, approximately one kilometer away.

The Ōishi clan was forced to submit to Hōjō Ujiteru, who made Takiyama Castle his field headquarters for the conquest of Musashi.

However, the true purpose of the attack was feint in an attempt to draw off Hōjō forces from Shingen's real target, which was Odawara Castle.

Although Shingen managed to encircle and threaten Odawara for a week, he eventually gave up and returned to Kai Province, and the forces at Takiyama Castle were also withdrawn.

Furthermore, the location of the castle proved that it was not an obstruction for Takeda army to attack the Hōjō home territory at Odawara.