The station's parking lot and bus stops are accessed from Eastern Avenue NW, which runs along the DC–Maryland line.

Prior to the opening of Metrorail, the Baltimore and Ohio Railroad (B&O) operated commuter trains that served intra-DC locations, including Takoma Park (this service continues as MARC's Brunswick Line, although the closest station serving the area is in Silver Spring, Maryland).

Remnants of the Takoma Park B&O rail stop are visible to the west of the Metro station.

The separate accessible and general entrances are a relative rarity in the Washington Metro system; only Rosslyn and Tenleytown–AU stations share this feature.

[10] Like Brookland–CUA, Fort Totten, and Silver Spring, Takoma is located in the middle of the CSX Metropolitan Subdivision rail line.