Talakhamani was a Kushite King of Meroë during the second half of the 5th century BCE.

He may have been a son of Nasakhma and a younger brother of Malewiebamani.

According to an inscription in Kawa he died in his palace at Meroe.

[1] Talakhamani's name is etymologically identical with that of King Talakhidamani, who ruled seven centuries later in the late 3rd or early 4th century AD.

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