Talas Region (Kyrgyz: Талас облусу, romanized: Talas oblusu; Russian: Таласская область, romanized: Talasskaya oblast) is a region (oblast) of Kyrgyzstan.

At the eastern end, the Talas Ala-Too Range splits off and marks the southern border.

The main highway (A361) enters from the east over the Ötmök Pass (Can become impassible during winter due to weather) and goes down the valley to Taraz in Kazakhstan.

Near the valley's mouth at Kyzyl-Adyr, one road goes north toward Taraz and the other south over the Kara-Buura Pass to Jalal-Abad Province.

[2] According to the 2009 Census, the ethnic composition of the Talas Region (de jure population) was:[4]