Talbot is nondenominational and known for its conservative theological positions, particularly its historical adherence to biblical inerrancy.

[1] In 1952, during the last year of his second term as Biola's president, Louis Talbot worked to establish a fully accredited theological seminary.

In 1981, the seminary's name was changed to "Talbot School of Theology" when Biola moved from college to university status.

[2] Talbot is known for its conservative theology, especially related to the doctrine of biblical inerrancy and premillennial eschatology.

Phase One added a new 30,617-square-foot (2,844.4 m2) building adjacent to Feinberg Hall, named Talbot East.