It stars Sophie Wilde, Alexandra Jensen, Joe Bird, Otis Dhanji, Miranda Otto, Zoe Terakes, Chris Alosio, Marcus Johnson, and Alexandria Steffensen.

Sometime later, 17-year-old Mia is struggling with the second anniversary of her mother Rhea's death by an accidental sleeping pill overdose and her distant relationship with her father, Max.

To prevent spirits from binding themselves to that person, someone else must end the possession before 90 seconds by pulling away the embalmed hand and blowing out a candle to cut the connection.

Mia uses the hand to contact Rhea, who insists that her death was accidental and that she needs to help Riley, who is still possessed and attempts suicide every time he returns to consciousness.

At home, Max reveals that Rhea's death was not an accident and reads her suicide note to Mia, apologizing for hiding the truth from her.

Mia finds herself in the hospital, where she sees a fully recovered Riley talking to Jade and Sue while Max leaves in an elevator.

She grabs it and is suddenly summoned to a house party in Greece, where a partygoer holding her hand is urged to speak and tells Mia, "I let you in".

[4][5] Directors Danny and Michael Philippou worked closely with producer Samantha Jennings, one of the co-founders of production company Causeway Films, who is familiar with Adelaide.

[25] On 9 August, the Kuwaiti authority formally announced the ban of both Talk to Me and American comedy film Barbie (which has an underlying feminist theme, as well as a transgender actress), claiming that it was to protect "public ethics and social traditions".

[29][30] In the United States and Canada, Talk to Me was released alongside Haunted Mansion, and was originally projected to gross $4–5 million from 2,340 theaters in its opening weekend.

The website's consensus reads: "With a gripping story and impressive practical effects, Talk to Me spins a terrifically creepy 21st-century horror yarn built on classic foundations.

[32] Jeannette Catsoulis of The New York Times wrote, "Distinguished by wonderfully gooey practical effects and deeply distressing visual jolts (especially when young Riley falls under the hand's malignant influence), Talk to Me has a hurtling energy that's often violent but never purposefully cruel."

More than just a great scream queen, she makes vivid sense of Mia's ravaged emotions, revealing her to be a captive less to the spirit realm than to her own inconsolable grief.

"[39] Jake Wilson of The Sydney Morning Herald gave the film 3½ out of 4 stars, writing, "The grim prologue leaves little doubt that horrible things are going to happen to people we're asked to care about – and while the ending may not fully satisfy the emotional expectations that have been built up, better too few comforting explanations than too many.

"[41] David Rooney of The Hollywood Reporter praised the film, saying that it "deftly stitches its deepest fears around the idea that grief and trauma can be open invitations to predatory forces from the great beyond.

Rooney also applauded the performances, writing, "While the predominantly young cast is solid, especially Bird as Riley, talented newcomer Wilde does the heaviest dramatic lifting.

"[44] In August 2023, Danny and Michael Philippou revealed that they had already completed principal photography on a prequel short film, with the story exploring Duckett's backstory which leads into the character's introduction in the original movie.