Talkha (Arabic: طلخا  pronounced [ˈtˤɑlxɑ]) is a city in Dakahlia Governorate, Egypt.

The city is located on the west bank of the Damietta,[2] a distributary of the Nile in the Delta region.

Talkha is situated opposite the city of Mansoura on the Damietta.

Together, the two cities form an agglomeration.

Talkha is classified within the Köppen climate classification system as a hot desert (BWh).