Tallapoosa is a city in New Madrid County, Missouri, United States.

[7] According to the United States Census Bureau, the city has a total area of 0.45 square miles (1.17 km2), all land.

There were 77 housing units at an average density of 171.1 per square mile (66.1/km2).

The racial makeup of the city was 97.62% White, 1.79% Native American, and 0.60% from two or more races.

32.4% of all households were made up of individuals, and 14.7% had someone living alone who was 65 years of age or older.

The racial makeup of the city was 95.10% White, 1.47% Native American, and 3.43% from two or more races.

19.2% of all households were made up of individuals, and 9.6% had someone living alone who was 65 years of age or older.

About 42.6% of families and 48.4% of the population were below the poverty line, including 50.9% of those under the age of eighteen and 18.2% of those 65 or over.