[3] As of the 2011 India Census, the population of Talwandi Kalan was about 3500 persons living in about 550 households.
[3] The presence of trace elements Selenium and Fluorine in the water of Talwandi Kalan has resulted in lower incidence of dental caries in village children than children of neighboring villages Dhanansu and Bhatian, whose water lacks these elements.
The 2007 film, End of Abundance, a documentary filmed by two Canadians, explores the ecological crisis, poverty, and ending productivity in India through the eyes of a farmer and student in Talwandi Kalan.
[8] The film Jatt te Zameen[9] was shot in Talwandi Kalan mainly in properties owned by Dalip Singh Dhanoa (deceased) and Gurcharan Singh Dhanoa (now living in Calgary, AB, Canada) On 6 December 1988, Punjabi film actor Veerendra was shot and killed by terrorists during the filming of a movie in Talwandi Kalan.
The terrorists had opened fire on a house owned by the then-former Minister of India.