[1] In 1521 he accompanied Thomas Cajetan (whom the pope had sent to Hungary to preach a crusade against the Turks) to Buda as his interpreter.

In 1525 he became a member of the council of state and was sent by King Louis II to the diet of Speyer to ask for help in the imminent Turkish war.

During his absence the Mohács catastrophe took place, and Nádasdy only returned to Hungary in time to escort the queen-widow from Komárom to Pozsony.

In 1533 his jealousy of the dominant influence of Lodovico Gritti caused him to desert John for Ferdinand, to whom he afterwards remained faithful.

[1] He did his utmost to promote education, and the school which he founded at Újsziget, where he also set up a printing press, received a warm eulogy from Philip Melanchthon.