[8] Wilson's big break came in 2007 when she made her opera debut replacing Patricia Racette for the entire run of the HGO's opening production of the 2007–2008 season as Amelia in Verdi's Un ballo in maschera to critical success.
[11][12] She also appeared at the Canadian Opera Company (COC) in 2009–2010 as Amelia Grimaldi in Verdi's Simon Boccanegra, and as Elettra in Mozart's Idomeneo.
[13] In 2011 Wilson made her debut at Carnegie Hall singing the role of the Virgin Mary in Honegger’s Jeanne d'Arc au bûcher with conductor Marin Alsop leading the Baltimore Symphony Orchestra, and made her debut at the Los Angeles Opera as Miss Jessel in Britten's The Turn of the Screw.
[18] In 2013 she returned to Carnegie Hall to perform the role of Malwina in Heinrich Marschner's Der Vampyr with the American Symphony Orchestra.
[20] In 2015 she made her debut at the English National Opera as Leonora in Verdi's La forza del destino; a performance which earned her an Olivier Award nomination.