The Inspector General of Police in the Central Zone is G. Karthikeyan IPS South Zone having jurisdiction over 10 Districts (excluding Madurai City and Tirunelveli City) viz., Madurai Rural, Dindigul, Ramanathapuram, Sivagangai, Theni, Virudhunagar, Tuticorin, Tirunelveli Rural, Kanyakumari and Tenkasi.

These Special Units perform specific functions related to security, intelligence, criminal investigations and support services.

The Cyber Crime Investigation Centre was notified as a police station with wider power and jurisdiction across the state.

Victims of any cyber financial fraud can contact the helpline to block and revert the money transferred to criminals.

In the financial year 2021 more than ₹3 crore (US$350,000) were recovered by Tamil Nadu police based on complaints of cyber crime.

[14] The Tamil Nadu Police has faced severe criticism for acts of misconduct, corruption, caste bias, and custodial deaths.

The CBI investigated the case on direction of the Madras High Court and filed report that 108 policemen were guilty in abetting the assault on innocent villagers.

The police raid was reported to target the material prosperity of the Pallars, on the orders of upper caste officials.

The entire team in the Sathankulam police station Tamil nadu, including those in other ranks, have been transferred to other locations.

[24][25] In 2021, the Chennai Police intervened in a case regarding a lesbian couple, who willingly fled their houses fearing interrogation and harassment.

[27] Furthermore, in the interim ruling, Judge Venkatesh prohibited Conversion Therapy, besides suggesting comprehensive measures to sensitize the society and remove prejudices against the LGBTQIA+ community.