[2] Karsian began her career appearing in episodes of Married... with Children, Who's the Boss?, Designing Women, Walker, Texas Ranger, and The X Files, along with recurring roles on the short-lived sitcoms Baby Talk, and Life's Work.
In 2000s, Karsian also played many small parts on television series such as NYPD Blue, Desperate Housewives, CSI: Crime Scene Investigation, and Prison Break.
[3] Karsian was regular cast member in the unaired HBO series, 12 Miles of Bad Road starring Lily Tomlin and Mary Kay Place.
Her film credits include The Number 23, Single White Female, Envy, and Boys Life 3.
[6] Karsian has co-written and co-starred with Andrea Grano in the 2014 independent comedy film BFFs, which featured her mother, Pat Carroll.