Tarbell Brook is a 10.1-mile-long (16.3 km)[1] stream located in southwestern New Hampshire and northern Massachusetts in the United States.

Tarbell Brook rises in the western part of Rindge, New Hampshire, at the outlet of Pearly Lake,[2] and flows south to the Damon Reservoirs.

The brook then passes into Winchendon, Massachusetts, reaching the Millers River approximately 2 miles (3 km) west of the town center.

It bears the name of Lieutenant Samuel Tarbell (1744-1828), a Revolutionary War Minuteman who settled in Rindge with his wife Beatrice Carter in 1773, soon thereafter building a watermill at the outflow of Pearly Lake (formerly known as Tarbell Pond).

Although the mill is long gone, Tarbell's Cape Cod style house nearby still presides over Route 119.