[4] Although first mentioned in 1507,[5] Tauragė did not receive its city charter until 1924, and its coat of arms (a silver hunting horn in a red field) until 1997.

Karšuva, the region which existed in these lands, was different because the peoples had the blood of the Kuršiai (Curonians) and Lamatiečiai (Lamatians), two nearby Baltic tribes.

Even the origin of the name Karšuva (Carsovia) can be linked to the ethnonym Kuršiai (Curonians), which is written as Cori, Corres, Kauren in old historical sources.

It is possible that in the end of the 13th c. and the start of 14th c., when Skalva suffered heavy casualties, Samogitians, supported by the rulers of the Grand Duchy of Lithuania, tried to push to the southwest.

At that time northern parts of Skalva, which were left for Lithuania, was inhabited by Samogitians, because most of the Scalovians were killed or fled during the attacks of the Order.

From 1691 until 1793, Tauragė belonged to Brandenburg-Prussia (the Kingdom of Prussia from 1701), after the marriage of Margrave Ludwig of Brandenburg to Princess Ludwika Karolina Radziwiłł.

On December 30, 1812, the Prussian General Yorck, signed the Convention of Tauroggen, declaring his troops neutral, that effectively ended the fragile Franco-Prussian alliance during the French invasion of Russia.

On September 9, 1927, the rebellion against the authoritarian rule of President Antanas Smetona broke out in Tauragė, but the revolt was quickly suppressed.

When Operation Barbarossa commenced on June 22, 1941, the Soviets retreated, and Tauragė was captured by the German Wehrmacht after heavy bombing on the same day.