Tavazzano con Villavesco (Lodigiano: Tavasàn cun Vilavésch) is a comune (municipality) in the Province of Lodi in the Italian region Lombardy, located about 35 kilometres (22 mi) southeast of Milan and about 9 kilometres (5.6 mi) northwest of Lodi.

Tavazzano con Villavesco borders the following municipalities: Mulazzano, Casalmaiocco, Lodi, Montanaso Lombardo, Sordio, San Zenone al Lambro and Lodi Vecchio.

It is served by Tavazzano railway station.

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