The university was founded in 1992 by Petre Shotadze, in whose honor it was posthumously renamed.

The Tbilisi Medical Academy (TMA) was established in 1992 by Petre Shotadze, a distinguished Georgian physician and paediatric surgeon.

Shotadze, a graduate of Tbilisi State Medical University in 1970, dedicated his entire doctoral, scientific, and academic career to the Tbilisi State Institute of Postgraduate Education for Physicians.

Within this institution, he progressed from being a postgraduate student to eventually becoming the Head of Pediatric Surgery and later the Rector.

Since its establishment, TMA has produced over 1500 graduates, many of whom have found successful employment in prominent Georgian and international hospitals, universities, and scientific centres.