Teófimo López vs. George Kambosos Jr. was a lightweight professional boxing match between unified WBA (Super), IBF, WBO, and The Ring lightweight champion Teófimo López, and IBF mandatory challenger George Kambosos Jr.[1] The fight took place on November 27, 2021, at the Hulu Theater, and was broadcast live exclusively on the streaming service DAZN.

[4][5] He was also called out by fellow American lightweight Devin Haney, as well as by Kambosos Jr., who had beaten Lee Selby to become the mandatory challenger to López's IBF title.

[9] On May 12, the bout was rescheduled for June 19, with Holyfield vs. McBride being removed from the undercard, before once again being pushed back to August 14, due to López testing positive for COVID-19.

[11] This proved controversial, because at the time Australia was in lockdown, which would have forced the champion López to arrive in the country at least 2 weeks beforehand and cut weight while in government-mandated isolation.

[12] On August 15, Triller co-founder Ryan Kavanaugh announced that he was trying to find a venue for the fight in Saudi Arabia or the United Arab Emirates.