The game is based on the television show Teen Titans.

Tired of the Teen Titans defeating him, Brother Blood decides to make clones of them to do his bidding.

The Teen Titans must hunt down his students and get their DNA back.

The game's boss characters are Gizmo, Jinx, Mammoth, and Brother Blood.

[3] A sequel, Teen Titans 2: The Brotherhood's Revenge, often shortened to simply Teen Titans 2, was released exclusively in North America for the Game Boy Advance on October 23, 2006.